Ipratropium bromide

07/04/2009 16:24

Ipratropium bromide

Brand Name: Alti-Ipratropium (CAN), Apo-Ipravent (CAN), Atrovent, Novo-Ipramide (CAN)


Pregnancy Category B

Drug classes: Anticholinergic, Antimuscarinic agent, Parasympatholytic



Therapeutic actions

Anticholinergic, chemically related to atropine, which blocks vagally mediated reflexes by antagonizing the action of acetylcholine.




· Bronchodilator for maintenance treatment of bronchospasm associated with COPD (solution, aerosol)

· Symptomatic relief of rhinorrhea associated with perennial rhinitis, common cold (nasal spray)




· Contraindicated with hypersensitivity to atropine or its derivatives, acute episodes of bronchospasm.

· Use cautiously with narrow-angle glaucoma, prostatic hypertrophy, bladder neck obstruction, pregnancy, lactation.



Adverse effects

Nervousness, dizziness, headache, fatigue, insomnia, blurred vision, Nausea, GI distress, dry mouth, Cough, exacerbation of symptoms, hoarseness, Palpitations, rash



Nursing considerations

· Protect solution for inhalation from light. Store unused vials in foil pouch.

· Ensure adequate hydration, provide environmental control (temperature) to prevent hyperpyrexia.

· Have patient void before taking medication to avoid urinary retention.

· Teach patient proper use of inhalator.